Objectives: We pretend to evaluate the prognosis of patients who underwent surgery for invasive bladder cancer and make a correlation with the traditional prognostic factors
Methods: Between 2011-2014, 50 patients underwent radical cystectomy. We reviewed all the informatics processes. The effect of various prognostic factors was evaluated by uni and multivariate analyses.
Results: A total of 50 patients were included in the study and were followed for a median period of 16,5 months after surgery. The overall 1 year survival and 2 year survival was 68% and 46% respectively. The overall 1 year and 2 years survival rates of patients with disease limited to the bladder T2NO were 73.9% and 60.9% and of patients with disease extending beyond the bladder T3NO 63% and 33% respectively. Only one of the factors studied was found to be significantly associated with overallsurvival: the disease recurrence after 12-month follow-up. No association was found between: smoking habits, gender, variant histology, co-morbidity (Charlson 6-11) and adjuvant chemotherapy.
Conclusions: The disease recurrence after 12-month follow-up was found to be the strongest factor associated with overall survival. Some classical factors, such as TMN-stage, co-morbidity, that were reported to predict overall and disease-free survival after surgery don’t have a significant association in our work. This might be important in selecting some patients to cystectomy, where we could be over predicting overall survival.