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From 27 to 53 % of the patients who have undergone radical therapy - prostatectomy (RP) or radiotherapy (RT) for prostate cancer (PC) can have biochemical recurrence. One must note that the number of reasons for performing prostatectomy in case of localized and low-differential prostate cancer is growing which might cause the increase in the number of recurrences.
We have studied 4 cases of oligometastatic disease (OMD)of prostate cancer in patients who have undergone radical prostatectomy in various hospitals: 3 patients with single metastasis in sternum and 1 patient with 3 metastasis in ribs. The examination was necessitated by the occurrence of biochemical recurrence - PSA >0,2 ng/ml. PSA level ranged from 2,4 ng/ml to 4,3 ng/ml. Positron Emission Tomography (PET/CT) with 11C-choline was made to all 4 patients. There were diagnosed as having OMD only with the use of PET scan. All of the patients have undergone radiofrequency ablation (RFA) with CT- navigation and ADT: triptorelin during 3 months after the RFA. For all patients 1-year recurrence-free survival was estimated.
During the 1 year follow-up after salvage therapy for OMD of PC nobody have had a recurrence which means that 1 year recurrence-free survival rate was 100%. Hospital stay have had 2 days. There were no complications observed. PSA level during follow-up period did not exceed 0,2 ng/ml/
We suppose that RFA is the reasonable method of treatment of bone metastatic disease after RP in case of OMD. PET/CT with choline can be used as a method of diagnosing OMD of PC after RP. The histological verification of a OMD of PC is not obligatory, and rather it can arbitrate in controversial cases.
