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The finding of metachronous malignant brain tumor in patient with a metastatic prostate cancer is not frequent and diagnostic evaluation can be challenging.
We describe a 68 years old patient diagnosed initially with a prostate cancer at the stage of bone metastasis. After one year of androgen deprivation, there was a complete clinical, radiological and biological remission. we decide de give radiotherapy to the prostate and pelvis.
one year later, the patient presented a right hemibody deficiency with a brain tumor surrounded with oedema at the CT scan.
The MRI showed an aspect of primitive brain tumor.
A stereotactic brain biopsy showed a glioblastoma multiforme
He had chemo-radiation for his brain tumor.
he is still alive after six months from his GBM treatment.
Prostate cancer has generally a good prognosis, but in our case, even with complete remission, the appearence of a glioblastoma has worsened the QoL and the estimated survival.