Urothelial carcinomas (UC) are the fourth most common tumours. Urothelial carcinomas of the upper urinary tract are uncommon and account for only 5-10% of UCs. In Spain the incidence of Upper Urinary Tract Urothelial Carcinoma is 3,14/100000 inhabitants. In 17% of cases, concurrent bladder cancer is present.
Rewiew the epidemiology of urothelial carcinomas the upper urinary tract of our health area. We also want to know the personal history of bladder carcinoma in this patients.
Materials and methods:
We have been made a retrospective review of all the patients diagnoses of upper urinary tract urothelial carcinoma between 2015 to 2018 in our health area. The variables included were gender, age, weight, height, BMI and tobacco exposure. We also value the personal history of presence of bladder cancer in this population and the histological data.
We diagnoses 43 cases of upper Urinary Tract Urothelial Carcinoma between 2015 and 2018. The incidence by gender was 86,7% males and 13,3% female, the mean age of presentation was 68 years [ 47- 86 years ]. The mean weight was 79 kg [66-105kg] and the mean height was 170cm [157-183cm], with a mean BMI 27 [22-31,70]. In our population we had 13,3% smokers, 46,7% ex-smokers and 26,7% no tobacco exposure. In 9 patients (21%) we found a medical history of bladder cancer. The histological data were non-muscle-invasive bladder cancer (urothelial carcinoma) in all the patients (33,3 % low grade and 66,6% high grade). All the patients were treated with laparoscopy radical nephroureterectomy.
As we know tobacco exposure is the most important risk factor of urothelial carcinoma and we need to reduce the incidence in our population ( 60% patients with tobacco exposure). Also our poblation have a very high BMI and this is another point to improve to have a better recovery after the surgery.
In a 21% of patients we found a personal history of bladder carcinoma. For that reason is very important to study the upper urinary tract in all the patients with bladder carcinoma in order to make an early diagnosis.
It is very important to know the demographic variables of our patients in order to carry out preventive health actions that improve the prognosis of our patients.